| 2型糖尿病患者胰腺MRI扩散加权成像初步研究 |
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| 引用本文： | 谢万猛,陈军,汪军,谢新佳.2型糖尿病患者胰腺MRI扩散加权成像初步研究[J].CT理论与应用研究,2016,25(5):563-569. |
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| 作者姓名： | 谢万猛 陈军 汪军 谢新佳 |
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| 作者单位： | 1. 武汉大学人民医院放射科, 武汉 430060; |
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| 摘 要： | 目的:探讨MRI扩散加权成像(DWI)在2型糖尿病患者的胰腺检查应用价值。方法:取纳入标准的75例2型糖尿病患者,根据病程分为三组:<2年、2~10年、>10年。同时选取25例健康人群作为健康对照组。采用MRI平扫、多期动态增强扫描及DWI检查测量患者胰腺的扩散系数(ADC),观察糖尿病患者胰腺的MRI及DWI信号表现特征。结果:DWI检查测量健康对照组、糖尿病<2年、2~10年、>10年三组患者胰腺体部的ADC值,取b值500 mm2/s时,分别测量每组的ADC均值为(2.00±0.17)×10-3 mm2/s,(1.94±0.09)×10-3 mm2/s,(1.86±0.13)×10-3mm2/s,(1.77±0.25)×10-3 mm2/s,与健康对照组相比,P值分别为0.023、0.010、0.008,两者差异具有统计学意义(P<0.05)。75例糖尿病患者MRI检查胰腺,1例追踪确诊为胰腺癌。结论:糖尿病患者胰腺DWI信号随病程延长而逐渐变化,能反应胰腺细胞功能改变,具有一定的临床参考价值,具有对早期单纯表现为糖尿病的胰腺癌患者进行筛查的潜能。
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| 关 键 词： | 糖尿病 胰腺 磁共振成像 扩散加权成像(DWI) 表观扩散系数 |
| 收稿时间： | 2016-02-03 |
A Primary Study of Magnetic Resonance Imaging-diffusion Weighted Imaging of Pancreas in Type 2 Diabetic Mellitus Patients |
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| XIE Wan-meng,CHEN Jun,WANG Jun,XIE Xin-jia.A Primary Study of Magnetic Resonance Imaging-diffusion Weighted Imaging of Pancreas in Type 2 Diabetic Mellitus Patients[J].Computerized Tomography Theory and Applications,2016,25(5):563-569. |
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| Authors: | XIE Wan-meng CHEN Jun WANG Jun XIE Xin-jia |
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| Affiliation: | 1. Department of Radiology, Renmin Hospital of Wuhan University, Wuhan 430060, China;2. Department of Radiology, Suizhou Central Hospital of Hubei Provinve, Suizhou 441300, China |
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| Abstract: | Objective: To investigate the value of MRI diffusion weighted imaging(DWI) in the diagnosis of pancreatic examination in patiens with type 2 diabetes mellitus. Methods: 75 patients with diabetic patients were divided into 3 groups according to the duration of the patients, 2 years2~10, 10 years. At the same time, 25 healthy people were selected as the control group. The diffusion coefficient (ADC) ofpancreatic lesions was measured by MRI scan, and DWI scan, and the imaging features of MRI and DWI were observed. Results:DWI examination and measurement of healthy control groupand the ADC values of pancreatic lesions in the three groups were (2.00±0.17)×10-3mm2/s, (1.94±0.09)×10-3mm2/s, (1.86±0.13)×10-3mm2/s,(1.77±0.25)×10-3 mm2/s.Compared with healthy controls, the P values were 0.023, 0.010, 0.008, and the difference was statistically significant between the two groups. 75 cases of diabetic patients with MRI examination of the pancreas, 1 case were eventually diagnosedaspancreatic cancer Conclusion: The DWI signal of pancreas in diabetic patients gradually decreased with the extension of the course. Some functional changes of the pancreatic cells.Screening earlypatients withpancreatic cancerwhosemanifestationwas just as diabetic. |
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| Keywords: | diabetes mellitus pancreas MRI diffusion weighted imaging ADC |
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